David Ignatius: How did covid-19 begin? Its initial origin story is shaky.

作者：David Ignatius  来源：Washington Post

The story of how the novel coronavirus emerged in Wuhan, China, has produced a nasty propaganda battle between the United States and China. The two sides have traded some of the sharpest charges made between two nations since the Soviet Union in 1985 falsely accused the CIA of manufacturing AIDS.

U.S. intelligence officials don’t think the pandemic was caused by deliberate wrongdoing. The outbreak that has now swept the world instead began with a simpler story, albeit one with tragic consequences: The prime suspect is “natural” transmission from bats to humans, perhaps through unsanitary markets. But scientists don’t rule out that an accident at a research laboratory in Wuhan might have spread a deadly bat virus that had been collected for scientific study.

“Good science, bad safety” is how Sen. Tom Cotton (R-Ark.) put this theory in a Feb. 16 tweet. He ranked such a breach (or natural transmission) as more likely than two extreme possibilities: an accidental leak of an “engineered bioweapon” or a “deliberate release.” Cotton’s earlier loose talk about bioweapons set off a furor, back when he first raised it in late January and called the outbreak “worse than Chernobyl.”

President Trump and Secretary of State Mike Pompeo added to the bile last month by describing the coronavirus as the “Chinese virus” and the “Wuhan virus,” respectively.

China dished wild, irresponsible allegations of its own. On March 12, Chinese foreign ministry spokesman Lijian Zhao charged in a tweet: “It might be [the] US army who brought the epidemic to Wuhan.” He retweeted an article that claimed, without evidence, that U.S. troops might have spread the virus when they attended the World Military Games in Wuhan in October 2019.

China retreated on March 22, when Ambassador to the United States Cui Tiankai told “Axios on HBO” that such rumors were “crazy” on both sides. A State Department spokesman said Cui’s comment was “welcome,” and Trump and Chinese President Xi Jinping pledged in a March 27 phone call to “focus on cooperative behavior,” a senior administration official told me.

To be clear: U.S. intelligence officials think there’s no evidence whatsoever that the coronavirus was created in a laboratory as a potential bioweapon. Solid scientific research demonstrates that the virus wasn’t engineered by humans and that it originated in bats.

But how did the outbreak occur? Solving this medical mystery is important to prevent future pandemics. What’s increasingly clear is that the initial “origin story” — that the virus was spread by people who ate contaminated animals at the Huanan Seafood Market in Wuhan — is shaky.

Scientists have identified the culprit as a bat coronavirus, through genetic sequencing; bats weren’t sold at the seafood market, although that market or others could have sold animals that had contact with bats. The Lancet noted in a January study that the first covid-19 case in Wuhan had no connection to the seafood market.

There’s a competing theory — of an accidental lab release of bat coronavirus — that scientists have been puzzling about for weeks. Less than 300 yards from the seafood market is the Wuhan branch of the Chinese Center for Disease Control and Prevention. Researchers from that facility and the nearby Wuhan Institute of Virology have posted articles about collecting bat coronaviruses from around China, for study to prevent future illness. Did one of those samples leak, or was hazardous waste deposited in a place where it could spread?

Richard Ebright, a Rutgers microbiologist and biosafety expert, told me in an email that “the first human infection could have occurred as a natural accident,” with the virus passing from bat to human, possibly through another animal. But Ebright cautioned that it “also could have occurred as a laboratory accident, with, for example, an accidental infection of a laboratory worker.” He noted that bat coronaviruses were studied in Wuhan at Biosafety Level 2, “which provides only minimal protection,” compared with the top BSL-4.

Ebright described a December video from the Wuhan CDC that shows staffers “collecting bat coronaviruses with inadequate [personal protective equipment] and unsafe operational practices.” Separately, I reviewed two Chinese articles, from 2017 and 2019, describing the heroics of Wuhan CDC researcher Tian Junhua, who while capturing bats in a cave “forgot to take protective measures” so that “bat urine dripped from the top of his head like raindrops.”

And then there’s the Chinese study that was curiously withdrawn. In February, a site called ResearchGate published a brief article by Botao Xiao and Lei Xiao from Guangzhou’s South China University of Technology. “In addition to origins of natural recombination and intermediate host, the killer coronavirus probably originated from a laboratory in Wuhan. Safety level may need to be reinforced in high risk biohazardous laboratories,” the article concluded. Botao Xiao told the Wall Street Journal in February that he had withdrawn the paper because it “was not supported by direct proofs.”

Accidents happen, human or laboratory. Solving the mystery of how covid-19 began isn’t a blame game, but a chance for China and the United States to cooperate in a crisis, and prevent a future one.

来源时间：2020/4/5   发布时间：2020/4/3

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